Medical oncology + infusion

Newport Beach Oncology & Infusion Center

Medical oncology, hematology, and infusion therapy delivered with USC Norris Comprehensive Cancer Center-level expertise — five minutes from Hoag Hospital and the Newport Beach waterfront.

Exterior of Keck Medicine of USC Newport Beach clinic at 330 Old Newport Blvd
Keck Medicine of USC Newport Beach reception and waiting area

The 330 Old Newport Blvd clinic is Keck Medicine of USC's dedicated medical oncology and infusion center for Orange County. It specializes in the treatment of blood disorders and cancer, offering the most effective and advanced therapies available in an environment built around the medical and emotional needs of patients and their families.

The state-of-the-art infusion center provides a quiet, restful environment for chemotherapy, immunotherapy, and supportive infusions. The on-site infusion drug laboratory uses the latest technology for the safe, sterile preparation of chemotherapy agents — no off-site compounding delays.

As part of a leading academic medical center, the clinic offers patients direct access to USC Norris clinical trials and weekly multidisciplinary tumor boards, where complex cases get a combined opinion from medical oncology, radiation oncology, surgical oncology, pathology, and radiology.

Services at this location

Medical oncology consultations

New-patient evaluations, second opinions, and active management for all solid tumors and blood cancers, including breast, lung, GI, GU, head and neck, melanoma, leukemia, lymphoma, and multiple myeloma.

Infusion therapy

Chemotherapy, immunotherapy, targeted therapy, biologics, blood products, hydration, iron, and supportive infusions in a quiet, dedicated infusion suite.

On-site oncology pharmacy

Chemotherapy and biologic agents prepared on-site by oncology-trained pharmacists, eliminating same-day off-site compounding delays.

Hematology

Evaluation and management of benign and malignant blood disorders — anemias, cytopenias, clotting disorders, lymphoma, leukemia, and myeloma.

Clinical trials access

Direct access to USC Norris Comprehensive Cancer Center trials, including immunotherapy, targeted therapy, and precision oncology protocols.

Telehealth visits

Established patients can complete follow-up, symptom check-in, and survivorship visits by secure video — useful for active-treatment patients who don't need to come in person.

Multidisciplinary tumor boards

Complex cases are presented at USC Norris tumor boards so the treatment plan reflects medical, surgical, radiation, pathology, and radiology input — not a single specialist's view.

Survivorship & supportive care

Coordinated survivorship plans plus access to nutrition, integrative medicine, social work, and financial counseling.

Physicians & care team at this clinic

10 providers practice at this location, including board-certified medical oncologists, hematologists, nurse practitioners, and physician assistants.

Awards & recognition

  • Licensed under USC Kenneth Norris Jr. Cancer Hospital — one of eight original NCI-designated Comprehensive Cancer Centers in the United States
  • USC Norris Comprehensive Cancer Center recognized by U.S. News & World Report Best Hospitals for Cancer (2025–26)
  • USC Norris recognized by U.S. News & World Report as High Performing for Leukemia, Lymphoma and Myeloma (2025–26)
  • Keck Hospital of USC earned five stars on the CMS 2026 quality star rating report — the highest rating possible
  • Keck Hospital of USC and USC-VHH each earned a Spring 2026 Leapfrog Hospital Safety Grade A
  • Norris Cancer Hospital — Leapfrog Group Top Hospital Award (multiple years)

Frequently asked questions

What should I bring to my first appointment?

Bring a photo ID, your insurance card, a list of current medications, and any imaging or pathology you've already had done (CDs of scans and pathology reports are most useful). Outside records help avoid duplicate testing.

How do I make an appointment or ask about a bill?

Call the clinic at (949) 646-6441 to schedule. For billing, the Business Office is at (818) 949-4055, and Keck Medicine also offers an online bill pay portal at pay.keckmedicine.org.

What insurance plans are accepted?

The clinic accepts most major insurance plans, including Anthem, Blue Cross, Blue Shield, Aetna, Cigna, UnitedHealthcare, Health Net, Medicare, and many Medicare Advantage plans. To confirm a specific plan call (818) 952-4730.

Are telehealth visits available?

Yes. Established patients can complete many follow-up, supportive-care, and survivorship visits by secure video — useful when an in-person visit isn't medically necessary.

Is the infusion center private?

Yes. Patients are treated in a quiet, restful infusion suite with private and semi-private bays. The on-site infusion pharmacy means chemotherapy is prepared in the same building, eliminating off-site compounding delays.

Also see: Newport Beach Radiation Oncology & Imaging for radiation oncology and advanced imaging.

Source: keckmedicine.org — bio, photo, and patient ratings republished for patient-navigation purposes. Cancer Answers OC is an independent patient-navigation resource and is not affiliated with Keck Medicine of USC. The official location page is at keckmedicine.org.