Simon Khagi, MD

Simon Khagi, MD, MBA, FACP, is the Medical Director of Neuro-Oncology at Hoag Family Cancer Institute and the Melinda Hoag Smith Endowed Chair for Neurological Oncology. Dr. Khagi is a board-certified medical oncologist with fellowship-training in neurological oncology. He specializes in brain and spinal cancer, advanced skin cancer, and lung cancer. His areas of research and expertise include immunotherapy, genomically-guided therapy, oncoloytic virotherapy, adoptive cell transfer, alternating tumor treatment fields and many others. He is regularly invited to give lectures and has been widely published with over fifty book chapters, peer-reviewed manuscripts, and abstracts.

Dr. Khagi has always felt a strong connection with patient and families battling cancer. His desire to help them motivated him to become an oncologist. According to Dr. Khagi, he considers quality and quantity of life as two sides of the same coin when supporting his patients. Valuing both is a cornerstone of the care he provides.

Prior to joining Hoag, Dr. Khagi was an Assistant Professor of Medicine at the Geisel School of Medicine at Dartmouth. He also served as an Associate Oncology Service Line Director and Regional Medical Director at Dartmouth Cancer Center in Southern New Hampshire. Prior to joining Dartmouth, Dr. Khagi was an Assistant Professor of Medicine and Neurosurgery at the University of North Carolina at Chapel Hill, as well as the Director of the Neuro-Oncology and Brain Metastases Program.

Dr. Khagi earned his Doctor of Medicine from the University of Missouri-Kansas City School of Medicine's combined/accelerated BA/MD program. He went on to complete his internal medicine training at Dartmouth Health, followed by a fellowship in hematology and medical oncology at Tufts Medical Center in Boston. He was a post-doctoral scholar under Dr. Brent Cochran, engaging in translational glioma stem cell biology and functional genomics research. Subsequently, he went on to complete subspecialty training in neuro-oncology at Duke University Hospital. He earned his Master of Business Administration degree from the Isenberg School of Management at the University of Massachusetts in Amherst.  He is an active member of multiple national organizations and is an inducted fellow of the American College of Physicians.