How much does chemotherapy cost in Orange County?

With in-network insurance, most Orange County patients pay only their plan's copays and coinsurance for chemotherapy — typically $0–$500 per infusion — up to their annual out-of-pocket maximum. Without insurance, a single chemotherapy infusion can range from roughly $1,000 to $12,000 depending on the drug.

Last updated: 2026-07-10 · Reviewed by Cancer Answers OC Care Coordination Team

Chemotherapy cost has two parts: the drug itself and the administration (infusion-suite time, nursing, supplies). Both are billed separately.

With an in-network commercial PPO or HMO plan, your share is limited by your deductible, coinsurance, and annual out-of-pocket maximum (capped at $9,450 individual / $18,900 family for ACA-compliant plans in 2024).

Medicare Part B covers infused chemotherapy at 80% after the Part B deductible; a Medigap plan typically picks up the remaining 20%.

Without insurance, ask the cancer center about cash-pay rates, manufacturer assistance programs, and nonprofit foundations — many patients qualify for substantial reductions.

Newport Beach providers featured on this site offer financial counseling before treatment starts so there are no surprise bills.