Answer
Does Medicare cover cancer immunotherapy?
Yes. Medicare covers FDA-approved immunotherapy (including checkpoint inhibitors) for cancer when medically necessary and prescribed by a Medicare-participating oncologist.
Last updated: 2026-07-10 · Reviewed by Cancer Answers OC Care Coordination Team
Original Medicare (Part B) covers infused immunotherapy administered in a physician's office or hospital outpatient setting.
Medicare Advantage (Part C) plans must cover at least what Original Medicare covers but typically require staying in-network.
Out-of-pocket costs depend on whether you have a Medigap policy or are enrolled in Medicare Advantage.
Coverage applies to approved immunotherapy drugs for indications consistent with FDA labeling or compendia-supported uses.