Answer
Does Blue Shield of California cover chemotherapy?
Yes. Blue Shield of California typically covers medically necessary chemotherapy, including infusion therapy and most oral chemotherapy, when delivered by in-network providers.
Last updated: 2026-07-10 · Reviewed by Cancer Answers OC Care Coordination Team
Blue Shield PPO, Trio HMO, Access+ HMO, and Medicare Advantage plans include chemotherapy benefits.
Infusion chemotherapy is covered under the medical benefit. Oral chemotherapy is typically covered under the pharmacy benefit.
Prior authorization is common for specialty oncology drugs and certain regimens.
Trio and Access+ HMO members should confirm the oncologist participates with their selected medical group.